shirt with caffeine molecule and coffee cup

This will affect how long caffeine can have its positive (or, if you can't sleep, negative) effects for.' clears caffeine from their system about four times slower than fast metabolizers. 'Fast metabolizers of caffeine who have the CYP1A2 AA genotype and slow metabolizers have the AC or CC genotypes. Caffeine metabolism is mainly determined by the cytochrome enzyme P-450 1A2 (CYP1A2),' Clarke said. 'Two of the genes which are thought to have the largest impact are CYP1A2 and ADORA2A. Whether we are slow or fast caffeine metabolizers may depend on our genes, Neil Clarke, an assistant professor in sport and exercise science at England's Coventry University, told Newsweek. People who burn through their caffeine faster will therefore be able to feel tired at the end of the day, while those who process it slower will still have some of their adenosine receptors filled and be less able to get tired in the evening, hitting sleep quality. 'So it is fairly well recognized now, in the scientific community, that people respond differently to caffeine-some of this is innate (determined by our genetic makeup), and some of it may be lifestyle-related (determined by how used to caffeine we are).' 'Broadly speaking, people can be fast or slow caffeine metabolizers, and also there is some evidence that people may be high or low sensitivity to the effects of caffeine,' Glen Davison, a professor in sport and exercise sciences at the University of Kent in England, told Newsweek. The speed at which your body metabolizes coffee may impact your quality of sleep.

Stock image of a tired woman surrounded by coffee.

Shirt with caffeine molecule and coffee cup